abstract：:The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

journal_title：Journal of neurophysiology

authors： Dahlem K,Valko Y,Schmahmann JD,Lewis RF

更新日期：2016-05-01 00:00:00

abstract：:In the rodent whisker system, a key model for neural processing and behavioral choices during active sensing, whisker motion is increasingly recognized as only part of a broader motor repertoire employed by rodents during active touch. In particular, recent studies suggest whisker and head motions are tightly coordina...

journal_title：Journal of neurophysiology

authors： Schroeder JB,Ritt JT

更新日期：2016-04-01 00:00:00

abstract：:Changes in the environment require rapid modification or inhibition of ongoing behavior. We used the stop-signal paradigm and intracranial recordings to investigate response preparation, inhibition, and monitoring of task-relevant information. Electrocorticographic data were recorded in eight patients with electrodes ...

journal_title：Journal of neurophysiology

authors： Fonken YM,Rieger JW,Tzvi E,Crone NE,Chang E,Parvizi J,Knight RT,Krämer UM

更新日期：2016-04-01 00:00:00

abstract：:We hypothesized that epilepsy affects the activity of the autonomic nervous system even in the absence of seizures, which should manifest as differences in heart rate variability (HRV) and cardiac cycle. To test this hypothesis, we investigated ECG traces of 91 children and adolescents with generalized epilepsy and 25...

journal_title：Journal of neurophysiology

authors： Sivakumar SS,Namath AG,Tuxhorn IE,Lewis SJ,Galán RF

更新日期：2016-04-01 00:00:00

abstract：:Interpretation of hemodynamic responses in epilepsy is hampered by an incomplete understanding of the underlying neurovascular coupling, especially the contributions of excitation and inhibition. We made simultaneous multimodal recordings of local field potentials (LFPs), firing of individual neurons, blood flow, and ...

journal_title：Journal of neurophysiology

authors： Saillet S,Quilichini PP,Ghestem A,Giusiano B,Ivanov AI,Hitziger S,Vanzetta I,Bernard C,Bénar CG

更新日期：2016-03-01 00:00:00

abstract：:The GABAergic neurons of the thalamic reticular nucleus (nRt) provide the primary source of inhibition within the thalamus. Using physiology, pharmacology, and immunohistochemistry in mice, we characterized postsynaptic developmental changes in these inhibitory projection neurons. First, at postnatal days 3-5 (P3-5), ...

journal_title：Journal of neurophysiology

authors： Pangratz-Fuehrer S,Sieghart W,Rudolph U,Parada I,Huguenard JR

更新日期：2016-03-01 00:00:00

abstract：:In many regions of the vertebrate brain, microcircuits generate local recurrent activity that aids in the processing and encoding of incoming afferent inputs. Local recurrent activity can amplify, filter, and temporally and spatially parse out incoming input. Determining how these microcircuits function is of great in...

journal_title：Journal of neurophysiology

authors： Liu Z,Ciarleglio CM,Hamodi AS,Aizenman CD,Pratt KG

更新日期：2016-03-01 00:00:00

abstract：:Paired-pulse transcranial magnetic stimulation (TMS) can be used to examine intracortical inhibition in primary motor cortex (M1), termed short-interval intracortical inhibition (SICI). To our knowledge, SICI has only been demonstrated in contralateral motor evoked potentials (MEPs). Ipsilateral MEPs (iMEPs) are assum...

journal_title：Journal of neurophysiology

authors： McCambridge AB,Stinear JW,Byblow WD

更新日期：2016-03-01 00:00:00

abstract：:Extraretinal information, such as corollary discharge (CD), is hypothesized to help compensate for saccade-induced visual input disruptions. However, support for this hypothesis is largely for one-dimensional transsaccadic visual changes, with little comprehensive information on the spatial characteristics. Here we sy...

journal_title：Journal of neurophysiology

authors： Jayet Bray LC,Bansal S,Joiner WM

更新日期：2016-03-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) is a noninvasive tool used to probe cognitive and affective processes. Although fMRI provides indirect measures of neural activity, the advent of fMRI has allowed for1) the corroboration of significant animal findings in the human brain, and2) the expansion of models to inc...

journal_title：Journal of neurophysiology

authors： Wang KS,Smith DV,Delgado MR

更新日期：2016-03-01 00:00:00

abstract：:The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...

journal_title：Journal of neurophysiology

authors： Kuroki S,Watanabe J,Nishida S

更新日期：2016-03-01 00:00:00

abstract：:The nucleus tractus solitarii (nTS) is the initial central termination site for visceral afferents and is important for modulation and integration of multiple reflexes including cardiorespiratory reflexes. Glutamate is the primary excitatory neurotransmitter in the nTS and is removed from the extracellular milieu by e...

journal_title：Journal of neurophysiology

authors： Matott MP,Ruyle BC,Hasser EM,Kline DD

更新日期：2016-03-01 00:00:00

abstract：:Many have recently questioned whether all levels of actions understanding, from lower kinematic levels to the higher goal or intention levels of action understanding, are processed in the action observation network (a network of neurons that are active during action execution and observation). A recent study by Wurm a...

journal_title：Journal of neurophysiology

authors： Marneweck M,Vallence AM

更新日期：2016-03-01 00:00:00

abstract：:Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction du...

journal_title：Journal of neurophysiology

authors： Bilaloglu S,Lu Y,Geller D,Rizzo JR,Aluru V,Gardner EP,Raghavan P

更新日期：2016-03-01 00:00:00

abstract：:In a recent study, Wang et al. (J Neurophysiol 113: 1989-2001, 2015) used a precision grip force control task to unveil the contribution of feedforward and feedback mechanisms to sensorimotor dysfunction in autism spectrum disorder (ASD). Impairment of both motor control mechanisms was observed, along with significant...

journal_title：Journal of neurophysiology

authors： Parma V,de Marchena AB

更新日期：2016-03-01 00:00:00

abstract：:Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...

journal_title：Journal of neurophysiology

authors： Long J,Tazoe T,Soteropoulos DS,Perez MA

更新日期：2016-03-01 00:00:00

abstract：:Recent experimental findings suggest that there may be rich physiological information embedded within the power spectrum of neurophysiological recordings, which, in addition to power in specific oscillatory frequencies, can be extracted with the appropriate model. This article reviews previous empirical and modeling r...

journal_title：Journal of neurophysiology

authors： Gao R

更新日期：2016-02-01 00:00:00

abstract：:Long-term potentiation (LTP) in rat spinal dorsal horn neurons was induced by electrical high-frequency stimulation (HFS) of afferent C fibers. LTP is generally assumed to be a key mechanism of spinal sensitization. To determine the contribution of skin and muscle afferents to LTP induction, the sural nerve (SU, pure ...

journal_title：Journal of neurophysiology

authors： Zhang J,Hoheisel U,Klein T,Magerl W,Mense S,Treede RD

更新日期：2016-02-01 00:00:00

abstract：:Perceptual decision making is often modeled as perfect integration of sequential sensory samples until the accumulated total reaches a fixed decision bound. In that view, the buildup of neural activity during perceptual decision making is attributed to temporal integration. However, an alternative explanation is that ...

journal_title：Journal of neurophysiology

authors： Carland MA,Marcos E,Thura D,Cisek P

更新日期：2016-02-01 00:00:00

abstract：:Animals and human beings sense and react to real/potential dangerous stimuli. However, the supraspinal mechanisms relating noxious sensing and nocifensive behavior are mostly unknown. The collateralization and spatial organization of interrelated neurons are important determinants of coordinated network function. Here...

journal_title：Journal of neurophysiology

authors： Leiras R,Martín-Cora F,Velo P,Liste T,Canedo A

更新日期：2016-01-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00

abstract：:Results from previous studies suggest that two-dimensional spatial patterns are processed similarly in vision and touch when the patterns are equated for effective size or when visual stimuli are blurred to mimic the spatial filtering of the skin. In the present study, we measured subjects' ability to perceive the sha...

journal_title：Journal of neurophysiology

authors： Cho Y,Craig JC,Hsiao SS,Bensmaia SJ

更新日期：2016-01-01 00:00:00

abstract：:A previous neurophysiological investigation demonstrated an increase in functional projections of expiratory bulbospinal neurons (EBSNs) in the segment above a chronic lateral thoracic spinal cord lesion that severed their axons. We have now investigated how this plasticity might be manifested in thoracic motoneurons ...

journal_title：Journal of neurophysiology

authors： Ford TW,Anissimova NP,Meehan CF,Kirkwood PA

更新日期：2016-01-01 00:00:00

abstract：:To examine the activity of somatosensory cortex (S1) neurons to self-generated shear forces on the index and thumb, two monkeys were trained to grasp a stationary metal tab with a key grip and exert forces without the fingers slipping in one of four orthogonal directions for 1 s. A majority (∼85%) of slowly adapting a...

journal_title：Journal of neurophysiology

authors： Fortier-Poisson P,Langlais JS,Smith AM

更新日期：2016-01-01 00:00:00

abstract：:In reaching to grasp an object, the arm transports the hand to the intended location as the hand shapes to grasp the object. Prior studies that tracked arm endpoint and grip aperture have shown that reaching and grasping, while proceeding in parallel, are interdependent to some degree. Other studies of reaching and gr...

journal_title：Journal of neurophysiology

authors： Rouse AG,Schieber MH

更新日期：2015-12-01 00:00:00

abstract：:The relative motion between the surface of an object and our fingers produces patterns of skin deformation such as stretch, indentation, and vibrations. In this study, we hypothesized that motion-induced vibrations are combined with other tactile cues for the discrimination of tactile speed. Specifically, we hypothesi...

journal_title：Journal of neurophysiology

authors： Dallmann CJ,Ernst MO,Moscatelli A

更新日期：2015-12-01 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults and is often refractory to antiepileptic medications. The medial entorhinal area (MEA) is affected in TLE but mechanisms underlying hyperexcitability of MEA neurons require further elucidation. Previous studies suggest that inputs from the pres...

journal_title：Journal of neurophysiology

authors： Abbasi S,Kumar SS

更新日期：2015-11-01 00:00:00

abstract：:Neurons in the silkmoth antennal lobe (AL) are well characterized in terms of their morphology and odor-evoked firing activity. However, their intrinsic electrical properties including voltage-gated ionic currents and synaptic connectivity remain unclear. To address this, whole cell current- and voltage-clamp recordin...

journal_title：Journal of neurophysiology

authors： Tabuchi M,Dong L,Inoue S,Namiki S,Sakurai T,Nakatani K,Kanzaki R

更新日期：2015-11-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:Secondary hyperalgesia is believed to be a key feature of "central sensitization" and is characterized by enhanced pain to mechanical nociceptive stimuli. The aim of the present study was to characterize, using EEG, the effects of pinprick stimulation intensity on the magnitude of pinprick-elicited brain potentials [e...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Mouraux A,Groneberg AH,Pfau DB,Treede RD,Klein T

更新日期：2015-11-01 00:00:00

abstract：:Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their ...

journal_title：Journal of neurophysiology

authors： Sturm JJ,Weisz CJ

更新日期：2015-11-01 00:00:00

abstract：:We have studied how rewards modulate the occurrence of microsaccades by manipulating the size of an expected reward and the location of the cue that sets the expectations for future reward. We found an interaction between the size of the reward and the location of the cue. When monkeys fixated on a cue that signaled t...

journal_title：Journal of neurophysiology

authors： Joshua M,Tokiyama S,Lisberger SG

更新日期：2015-11-01 00:00:00

abstract：:During object manipulation, grip force is coordinated with load force, which is primarily determined by object kinematics. Proximal arm kinematics may affect grip force control, as proximal segment motion could affect control of distal hand muscles via biomechanical and/or neural pathways. The aim of this study was to...

journal_title：Journal of neurophysiology

authors： Vermillion BC,Lum PS,Lee SW

更新日期：2015-10-01 00:00:00

abstract：:STX1 is a major neuronal syntaxin protein located at the plasma membrane of the neuronal tissues. Rodent STX1 has two highly similar paralogs, STX1A and STX1B, that are thought to be functionally redundant. Interestingly, some studies have shown that the distribution patterns of STX1A and STX1B at the central and peri...

journal_title：Journal of neurophysiology

authors： Wu YJ,Tejero R,Arancillo M,Vardar G,Korotkova T,Kintscher M,Schmitz D,Ponomarenko A,Tabares L,Rosenmund C

更新日期：2015-10-01 00:00:00

abstract：:It is not known how changes in skin mechanics affect the responses of cutaneous mechanoreceptors in the finger pads to compression forces. We used venous occlusion to change the stiffness of the fingers and investigated whether this influenced the firing of low-threshold mechanoreceptors to surfaces of differing stiff...

journal_title：Journal of neurophysiology

authors： Hudson KM,Condon M,Ackerley R,McGlone F,Olausson H,Macefield VG,Birznieks I

更新日期：2015-10-01 00:00:00

abstract：:Facial flushing in rosacea is often induced by trigger events. However, trigger causation mechanisms are currently unclear. This study tested the central hypothesis that rosacea causes sympathetic and axon reflex-mediated alterations resulting in trigger-induced symptomatology. Twenty rosacea patients and age/sex-matc...

journal_title：Journal of neurophysiology

authors： Metzler-Wilson K,Toma K,Sammons DL,Mann S,Jurovcik AJ,Demidova O,Wilson TE

更新日期：2015-09-01 00:00:00

abstract：:There is a great need to develop new approaches for rehabilitation of the upper limb after stroke. Robotic therapy is a promising form of neurorehabilitation that can be delivered in higher doses than conventional therapy. Here we sought to determine whether the reported effects of robotic therapy, which have been bas...

journal_title：Journal of neurophysiology

authors： Kitago T,Goldsmith J,Harran M,Kane L,Berard J,Huang S,Ryan SL,Mazzoni P,Krakauer JW,Huang VS

更新日期：2015-09-01 00:00:00

abstract：:It has been suggested that some cortically blind patients can process the emotional valence of visual stimuli via a fast, subcortical pathway from the superior colliculus (SC) that reaches the amygdala via the pulvinar. We provide in vivo evidence for connectivity between the SC and the amygdala via the pulvinar in bo...

journal_title：Journal of neurophysiology

authors： Rafal RD,Koller K,Bultitude JH,Mullins P,Ward R,Mitchell AS,Bell AH

更新日期：2015-09-01 00:00:00

abstract：:The effects of deep brain stimulation (DBS) on balance in people with Parkinson's disease (PD) are not well established. This study examined whether DBS randomized to the subthalamic nucleus (STN; n = 11) or globus pallidus interna (GPi; n = 10) improved compensatory stepping to recover balance after a perturbation. T...

journal_title：Journal of neurophysiology

authors： St George RJ,Carlson-Kuhta P,King LA,Burchiel KJ,Horak FB

更新日期：2015-09-01 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00